2022年論文研究成果

編號

作者

中心參與人員

標題

期刊名稱

ISSN

發表年

頁碼(起)

頁碼(迄)

DOI碼

1

山口浩史(Yamaguchi Hirohito)、許榮茂(Hsu,Jung-Mao)、楊文豪(Yang,Wen-Hao)、洪明奇(Mien-Chie Hung)*

洪明奇、楊文豪

Mechanisms regulating PD-L1 expression in cancers and associated opportunities for novel small-molecule therapeutics

Nature Reviews Clinical Oncology

(IF= 66.675)

 

2022

19

5

287

305

DOI: 10.1038/s41571-022-00601-9

2

游家鑫(Jiaxin Yu)、林秀姍(Hsiu-Hsien Lin)、曾坤浩(Kun-Hao Zeng)、田霓(Ni Tien)、薛博仁(Hsueh, Po-Ren)*、周德陽(Der-Yang Cho)*

周德陽

Direct prediction of ceftazidime-resistant Stenotrophomonas maltophilia from routine MALDI-TOF mass spectra using machine learning

Journal of Infection

(IF= 38.637)

 

2022

 

 

 

 

DOI: 10.1016/j.jinf.2022.09.005

3

(Feng L)、(Liu Z,)、(Li C)、(Li Z)、(Lou X,)、(Shao L)、(Wang Y,)、(Huang Y)、(Chen H,)、(Pang X)、(Liu S)、(He F)、(Zheng J,)、(Meng X)、(Xie P,)、(Yang G)、(Ding Y,)、(Wei M)、(Yun J)、洪明奇(Mien-Chie Hung)、(Zhou W,)、(Wahl DR)、(Lan P,)、(Tian J)*、(Wan X)*

洪明奇、陳曄

Development and validation of a radiopathomics model to predict pathological complete response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer: a multicentre observational study

Lancet Digital Health

(IF=36.615 )

 

2022

4

1

e8

e17

DOI: 10.1016/S2589-7500(21)00215-6

4

Chin-Yu Lin, YL Wang, Yu-Jen Chen, Chun-Te Ho, YH-Chi, LY Chan, GW Chen, Horng-Chaung Hsu, Dennis W Hwang, HC Wu*, Shih-Chieh Hung*

Shih-Chieh Hung

Collagen-binding peptides for the enhanced imaging, lubrication and regeneration of osteoarthritic articular cartilage.

Nature Biomedical Engineering

(IF= 29.234)

2157-846X

2022

410

 

1105

1117

DOI: 10.21203/rs.3.rs-87673/v1

5

(Yu M)、(Chen Z)、(Zhou Q)、(Zhang B)、(Huang J)、(Jin L)、(Zhou B)、(Liu S)、(Yan J)、(Li X)、(Zhang W)、(Liu C)、(Hu B)、(Fu P)、(Zhou C)、(Xu Y)、(Xiao Y)、(Zhou J)、(Fan J)、(Ren N)、洪明奇(Mien-Chie Hung)、(Guo L)、(Li H)*、(Ye Q)*

洪明奇

PARG inhibition limits HCC progression and potentiates the efficacy of immune checkpoint therapy

Journal of Hepatology

(IF=25.083 )

 

2022

77

1

140

151

DOI: 10.1016/j.jhep.2022.01.026

6

Chu YY, Chen MK, Wei Y, Lee HH, Xia W, Wang YN, Yam C, Hsu JL, Wang HL, Chang WC, Yamaguchi H, Jiang Z, Liu CX, Li CF, Nie L, Chan LC, Gao Y, Wang SC, Liu J, Westin SN, Lee S, Sood AK, Yang L, Hortobagyi GN, Yu D* and Hung MC*.

洪明奇

Targeting the ALK/CDK9-Y19 kinase cascade sensitizes ovarian and breast tumors to PARP inhibition via destabilization of the P-TEFb complex.

Nature Cancer

(IF=23.177 )

 

2022

3

10

1211

1227

DOI: 10.1038/s43018-022-00438-2

7

Satoru Sugimoto , Hebe Agustina Mena , Brian E Sansbury , Shio Kobayashi , Tadataka Tsuji , Chih-Hao Wang , Xuanzhi Yin , Tian Lian Huang , Joji Kusuyama , Sean D Kodani , Justin Darcy , Gerson Profeta , Nayara Pereira , Rudolph E Tanzi , Can Zhang , Thomas Serwold , Efi Kokkotou , Laurie J Goodyear , Aaron M Cypess , Luiz Osório Leiria , Matthew Spite , Yu-Hua Tseng

王志豪

Brown adipose tissue-derived MaR2 contributes to cold-induced resolution of inflammation

Nature Metabolism
(IF=19.95 )

 

2022

4

6

775

790

DOI: 10.1038/s42255-022-00590-0

8

(Wang YL,)、(Zhao WW)、(Bai SM,)、(Feng LL)、(Bie SY,)、(Gong L)、(Wang F,)、(Wei MB)、(Feng WX,)、(Pang XL)、(Qin CL,)、(Yin XK)、(Wang YN,)、(Zhou W)、(Wahl DR,)、(Liu Q)、(Chen M)*、洪明奇(Mien-Chie Hung)*、(Wan XB)*

洪明奇

MRNIP condensates promote DNA double-strand break sensing and end resection

Nature Communications

(IF=17.694 )

 

2022

13

1

2638

 

DOI: 10.1038/s41467-022-30303-w

9

Yi-Ing Chen, Chin-Chun Chang, Min-Fen Hsu, Yung-Ming Jeng, Yu-Wen Tien, Ming-Chu Chang, Yu-Ting Chang, Chun-Mei Hu*, Wen-Hwa Lee*

Wen-Hwa Lee

Homophilic ATP1A1 binding induces activin A secretion to promote EMT of tumor cells and myofibroblast activation

Nature communications

(IF=17.694 )

N/A(EISSN 2041-1723)

2022

13

1

2945

 

DOI: 10.1038/s41467-022-30638-4

10

(Tzu-Ping Ko)、王昱權(WANG YU-CHUAN)、(Chia-Shin Yang)、侯美慧(HOU,MEI-HUI)、陳朝榮(Chao-Jung Chen)、邱翊芳(Chiu, Yi-Fang)、陳曄(Chen,Yeh)*

陳曄

Crystal structure and functional implication of bacterial STING

Nature Communications

(IF=17.694 )

 

2022

13

1

1

13

DOI: 10.1038/s41467-021-26583-3

11

(Zhao X)、(Wei Y)、(Chu YY)、(Li Y)、(Hsu JM)、(Jiang Z)、(Liu C)、(Hsu JL)、(Chang WC)、(Yang R)、(Chan LC)、(Qu J)、(Zhang S)、(Ying H)、(Yu D)*、洪明奇(Mien-Chie Hung)*

洪明奇

Phosphorylation and Stabilization of PD-L1 by CK2 Suppresses Dendritic Cell Function

Cancer Research

(IF=13.678 )

 

2022

82

11

2185

2195

DOI: 10.1158/0008-5472.CAN-21-2300

12

吳承修(Wu, Chen-Shiou)、江秀梅(Chiang, Hsiu-Mei)、陳曄(Chen,Yeh)、陳崇宇(Chen, Chung Yu)、陳筱凡(Chen Hsiao-Fan)、蘇文琪(Wen-Chi Su)、王韋然(Wang, Wei-Jan)、(Chou UC)、張為超(Wei-Chao Chang)、王紹椿(Shao-Chun Wang)、洪明奇(Mien-Chie Hung)*

王紹椿、陳曄、洪明奇

Prospects of Coffee Leaf against SARS-CoV-2 Infection

International Journal of Biological Sciences

(IF=10.75 )

 

2022

18

12

4677

4689

DOI: 10.7150/ijbs.76058

13

王紹椿(Shao-Chun Wang)*、周怡彣、洪明奇(Mien-Chie Hung)*

王紹椿、洪明奇

Natural tannins as anti-SARS-CoV-2 compounds

International Journal of Biological Sciences

(IF=10.75 )

 

2022

18

12

4669

4676

DOI: 10.7150/ijbs.74676

14

Kai-Wen Hsu, Joseph Chieh-Yu Lai, Jeng-Shou Chang, Pei-Hua Peng, Ching-Hui Huang, Der-Yen Lee, Yu-Cheng Tsai, Chi-Jung Chung, Han Chang, Chao-Hsiang Chang, Ji-Lin Chen, See-Tong Pang, Ziyang Hao, Xiao-Long Cui, Chuan He, Kou-Juey Wu

許凱文

MTX-mediated nuclear N6-deoxyadenosine methylation promotes metastasis through activating multiple metastasis-inducing targets

 Genome Biology

(IF=17.906 )

 

2022

23

1

249

 

DOI: 10.1186/s13059-022-02819-3.

15

Wen-Hsin Lee, Xiaorui Chen, I-Ju Liu, Jiin-Horng Lee, Chun-Mei Hu, Han-Chung Wu, Sheng-Kai Wang, Wen-Hwa Lee*, Che Ma*

Wen-Hwa Lee

Structural basis of interleukin-17B receptor in complex with a neutralizing antibody for guiding humanization and affinity maturation

Cell Reports

2211-1247

2022

44

4

111555

 

DOI: https://doi.org/10.1016/j.celrep.2022.111555

16

(Wen Y)、(Chelariu-Raicu A)、(Umamaheswaran S)、(Nick AM)、(Stur E)、(Hanjra P)、(Jiang D)、(Jennings NB)、(Chen X)、(Corvigno S)、(Glassman D)、(Lopez-Berestein G)、(Liu J)、洪明奇(Mien-Chie Hung)、(Sood AK)*

洪明奇

Endothelial p130cas confers resistance to anti-angiogenesis therapy

Cell Reports

 

2022

38

4

110301

 

DOI: 10.1016/j.celrep.2022.110301

17

Yu-Huei Liu*, Chun-Mei Hu, Yuan-Sheng Hsu, Wen-Hwa Lee*

Yu-Huei Liu, Wen-Hwa Lee

Interplays of glucose metabolism and KRAS mutation in pancreatic ductal adenocarcinoma

Cell Death & Disease

2041-4889

2022

13

9

817

 

DOI: 10.1038/s41419-022-05259-w

18

Yu-Cheng Chin, Li-Xing Yang, Fei-Ting Hsu*, Che-Wei Hsu, Te-Wei Chang, Hsi-Ying Chen, Linda Yen-Chien Chen, Zi Chun Chia, Chun-Hua Hung, Wu-Chou Su, Yi-Chun Chiu, Chih-Chia Huang, Mei-Yi Liao

Fei-Ting Hsu

Iron chlorophyll-guided Fe3O4 nano-assembly and adoption of an advanced ferroptosis strategy to enhance photodynamic immunotherapy on bladder cancer.

Journal of Nanobiotechnology

1477-3155

2022

20

1

373

 

DOI: 10.1186/s12951-022-01575-7

19

山口浩史(Yamaguchi Hirohito)*、王紹椿(Shao-Chun Wang)、洪明奇(Mien-Chie Hung)*

王紹椿、洪明奇

Prospects of the potential strategies to improve the efficacy of anti-PD-1/PD-L1 therapy

Clinical and Translational Medicine

 

2022

12

5

803

 

DOI: 10.1002/ctm2.803

20

Zong-Shin Lin, Chiao-Chen Chung, Yu-Chia Liu, Chu-Han Chang, Hui-Chia Liu, Yung-Yi Liang, Teng-Le Huang, Tsung-Ming Chen, Che-Hsin Lee, Chih-Hsin Tang, Mien-Chie Hung and Ya-Huey Chen

Ya-Huey Chen

EZH2/ hSULF1 axis mediates receptor tyrosine kinase signaling to shape cartilage tumor progression

eLife

 2050-084X

2022

 under revision

 

 

 

 

21

Yueh-Shan Weng, I-Tsang Chiang, Jai-Jen Tsai, Yu-Chang Liu, Fei-Ting Hsu*

Fei-Ting Hsu

Lenvatinib synergistically promotes radiotherapy on hepatocellular carcinoma via inhibiting Src/STAT3/NF-kB mediated epithelial-mesenchymal transition and metastasis

International Journal of Radiation Oncology, Biology, Physics

0360-3016

2022

S0360-3016

22

03352-1

 

DOI: 10.1016/j.ijrobp.2022.09.060

22

(Satoru Sugimoto)、(Hebe Agustina Mena)、(Brian E Sansbury)、(Shio Kobayashi)、(Tadataka Tsuji)、王志豪(Wang, Chih-Hao)、(Xuanzhi Yin)、(Tian Lian Huang)、(Joji Kusuyama)、(Sean D Kodani)、(Justin Darcy)、(Gerson Profeta)、(Nayara Pereira)、(Rudolph E Tanzi)、(Can Zhang)、(Thomas Serwold)、(Efi Kokkotou)、(Laurie J Goodyear)、(Aaron M Cypess)、(Luiz Osorio Leiria)、(Matthew Spite)、(Yu-Hua Tseng)*

王志豪

Brown adipose tissue-derived MaR2 contributes to cold-induced resolution of inflammation,Nature Metabolism

Nature Metabolism

 

2022

4

6

775

790

DOI: 10.1038/s42255-022-00590-0

23

Lun-Yin Chou, Chun-Te Ho*, Shih-Chieh Hung*

Shih-Chieh Hung

Paracrine senescence of mesenchymal stem cells involves inflammatory cytokines and the NF-kB pathway.

Cells

0168-8278

2022

74

4

907

918

DOI: 10.1016/j.jhep.2020.09.030

24

顏加豪(Jia-hau Yen)、黃暐捷(Wei-Chieh Huang)、林淑卿(Shu-Ching Lin)、黃怡紋(Yi-Wen Huang)、邱琬婷、蔡嘉哲(Gregory J. Tsay)、洪明奇(Mien-Chie Hung)*、黃升騰(Sheng-Teng Huang)*

洪明奇、蔡嘉哲

Metabolic remodeling in tumor-associated macrophages contributing to antitumor activity of cryptotanshinone by regulating TRAF6-ASK1 axis

Molecular Therapy-Oncolytics

 

2022

22

26

158

174

DOI: 10.1016/j.omto.2022.06.008

25

游家鑫(Jiaxin Yu)、田霓(Ni Tien)*、劉玉晴、周德陽(Der-Yang Cho)、(Jia-Wen Chen)、(Yin-Tai Tsai)、(Yu-Chen Huang)、(Huei-Jen Chao)、陳朝榮(Chao-Jung Chen)*

周德陽

Rapid Identification of Methicillin-Resistant Staphylococcus aureus Using MALDI-TOF MS and Machine Learning from over 20,000 Clinical Isolates

Microbiology Spectrum

 

2022

 

 

 

 

DOI: 10.1128/spectrum.00483-22

26

王志豪(Wang, Chih-Hao)、王振宏(Wang, Chen-Hung)、洪本蓉、魏耀揮*

王志豪

Disruption of mitochondria-associated ER membranes impairs insulin sensitivity and thermogenic function of adipocytes,Frontiers in Cell and Developmental Biology

Frontiers in Cell and Developmental Biology

 

2022

10

 

955523

 

DOI: 10.3389/fcell.2022.965523

27

Onikanni Sun(Onikanni Sunday Amos)、(Bashir Lawal)、(Babatunji Emmanuel Oyinloye)、(Gomaa Mostafa-Hedeab)、(Mohammed Alorabi)、(Simona Cavalu)、(Augustine O. Olusola)*、王志豪(Wang, Chih-Hao)*、(Gaber El-Saber Batiha)

王志豪

Therapeutic efficacy of Clompanus pubescens leaves fractions via downregulation of neuronal cholinesterases/Na+-K+ATPase/IL-1 β, and improving the neurocognitive and antioxidants status of streptozotocin-induced diabetic rats,BIOMEDICINE & PHARMACOTHERAPY

Biomedicine & Pharmacotherapy

 

2022

148

 

112730

 

DOI: 10.1016/j.biopha.2022.112730

28

魏嵩泰(Sung-Tai Wei)、江忠穎(Jung-Ying Chiang)、王惠勵(Hwai-Lee Wang)、雷馥如(Fu-Ju Lei)、黃彥智(Yen-Chih Huang)、王啟仲(Chi-Chung Wang)、周德陽(Der-Yang Cho)、謝佳宏(Chia-Hung Hsieh)*

周德陽

Hypoxia-induced CXC chemokine ligand 14 expression drives protumorigenic effects through activation of insulin-like growth factor-1 receptor signaling in glioblastoma

Cancer Science

 

2022

 

 

 

 

DOI: 10.1111/cas.15587

29

劉良智(Liang-Chih Liu)、沈宜君(Shen, Yi-Chun)、王元良(Yuan-Liang Wang)、鄔宛蓉、張玲菊(Ling-Chu Chang)、陳雅惠(Ya-Huey Chen)、李權峻(Chuan-Chun Lee)*、王紹椿(Shao-Chun Wang)*

王紹椿、陳雅惠

Growth-promoting function of the cGAS-STING pathway in triple-negative breast cancer cells

Frontiers in Oncology

 

2022

12

 

851795

 

DOI: 10.3389/fonc.2022.851795

30

王元良(Yuan-Liang Wang)、鄔宛蓉、林裴樂(Pei-Le Lin)、沈宜君(Shen, Yi-Chun)、林佑哲(You-Zhe Lin)、李浤維(Li, Houng-Wei)、許凱文(Hsu, Kai-Wen)、王紹椿(Shao-Chun Wang)*

You-Zhe Lin, Kai-Wen Hsu , Shao-Chun Wang

The Functions of PCNA in Tumor Stemness and Invasion

International Journal of Molecular Sciences 

1422-0067

2022

23

10

5679

 

DOI: 10.3390/ijms23105679

31

何建宜(Chien-Yi Ho)、游家鑫(Jiaxin Yu)、王昱權(WANG YU-CHUAN)、(Yu-Chuan Lin)、邱翊芳(Chiu, Yi-Fang)、高敬彥(Gao, Jing-Yan)、賴姝蓉(Lai, Shu-Jung)、(Ming?Jen Chen)、黃偉謙(Huang, Wei-Chien)、田霓(Ni Tien)*、陳曄(Chen,Yeh)*

黃偉謙、陳曄

A Structural Comparison of SARS-CoV-2 Main Protease and Animal Coronaviral Main Protease Reveals Species-Specific Ligand Binding and Dimerization Mechanism

International Journal of Molecular Sciences

 

2022

23

10

5669

 

DOI: 10.3390/ijms23105669

32

Kung-Wen Lu,Tai-Jung Lu,Fu-Shin Chueh,Kuang-Chi Lai,Te-Chun Hsia, Shu-Fen Peng,Ching-Chang Cheng,Yu-Cheng Chou,and Fei-Ting Hsu*

Fei-Ting Hsu

Allyl Isothiocyanate (AITC) Induces Apoptotic Cell Death In Vitro and Exhibits Anti-Tumor Activity in a Human Glioblastoma GBM8401/luc2 Model

International Journal of Molecular Sciences

EISSN 1422-0067

2022

23

18

10411

 

DOI: 10.3390/ijms231810411

33

Syuan-Ling Lin, Chih-Yang Lin, Wei Lee, Chiao-Fang Teng, Woei-Cherng Shyu*, Long-Bin Jeng

Woei-Cherng Shyu

Mini Review: Molecular Interpretation of the IGF/IGF-1R Axis in Cancer Treatment and Stem Cells-Based Therapy in Regenerative Medicine

International Journal of Molecular Sciences

EISSN 1422-0067

2022

23

19

11791

 

DOI: 10.3390/ijms231911781

34

侯曼貞(Mann-Jen Hou)、陳曄(Chen,Yeh)、(Chen-Sheng Lin)、(Lidia A. Baltina)、(Ju-Ying Kan)、(Yan-Ting Tsai)、(Yan-Tung Kiu)、賴學洲(Hsueh-Chou Lai)、(Lia A. Baltina)、(Svetlana F. Petrova)、林振文(Lin, Cheng-Wen)*

陳曄

Glycyrrhizic Acid Derivatives Bearing Amino Acid Residues in the Carbohydrate Part as Dengue Virus E Protein Inhibitors: Synthesis and Antiviral Activity

International Journal of Molecular Sciences

 

2022

23

18

10309

 

DOI: 10.3390/ijms231810309

35

Chia-Hsin Liu, Shu-Hsuan Liu,Yo-Liang Lai, Yi-Chun Cho, Fang-Hsin Chen, Li-Jie Lin, Pei-Hua Peng, Chia-Yang Li, Shu-Chi Wang, Ji-Lin Chen, Heng-Hsiung Wu, Min-Zu Wu, Yuh-Pyng Sher, Wei-Chung Cheng, Kai-Wen Hsu

吳恒祥、許凱文

Using bioinformatics approaches to identify survival-related oncomiRs as potential targets of miRNA-based treatments for lung adenocarcinoma

Computational and Structural Biotechnology Journal

2001-0370

2022

20

 

4626

4635

DOI: 10.1016/j.csbj.2022.08.042

36

Chen-Chi Liu, Hsin-Hsien, Jiun-Han Lin, Ming-Chen Chiang, Tien-Wei Hsu, Anna Fen-Yau Li, David Hung-Tsang Yen, Han-Shui Hsu, Shih-Chieh Hung*

Shih-Chieh Hung

Esophageal cancer stem-like cells resist ferroptosis-induced cell death by active Hsp27-GPX4 pathway

Biomolecules

1554-8627

2022

under revision

 

 

 

DOI: 10.1126/sciadv.aaz4452

37

(Ye P)、(Chi X)、(Yan X)、(Wu F)、(Liang Z)、楊文豪(Yang,Wen-Hao)*

楊文豪

Alanine-Glyoxylate Aminotransferase Sustains Cancer Stemness Properties through the Upregulation of SOX2 and OCT4 in Hepatocellular Carcinoma Cells

Biomolecules

 

2022

12

5

668

 

DOI: 10.3390/biom12050668

38

(Luo S)、(Yang G)、(Ye P)、(Cao N)、(Chi X)、楊文豪(Yang,Wen-Hao)*、(Yan X)*

楊文豪

Macrophages Are a Double-Edged Sword: Molecular Crosstalk Between Tumor-Associated Macrophages and Cancer Stem Cells

Biomolecules

 

2022

12

6

850

 

DOI: 10.3390/biom12060850

39

Yuan-Sheng Hsu, Pei-Jung Wu, Yung-Ming Jeng, Chun-Mei Hu*, Wen-Hwa Lee*

Wen-Hwa Lee

Differential effects of glucose and N-acetylglucosamine on genome instability

American Journal of Cancer Research

2156-6976

2022

12

4

1556

1576

PMC9077085

40

陳筱凡(Chen Hsiao-Fan)、薛博仁(Hsueh, Po-Ren)、劉儼毅(Yen-Yi Liu)、陳曄(Chen,Yeh)、(Sui-Yuan Chang)、王韋然(Wang, Wei-Jan)、吳承修(Wu, Chen-Shiou)、(Ya-Min Tsai)、(Yu-Shu Liu)、蘇文琪(Wen-Chi Su)、(Yu-Chi Chou)、洪明奇(Mien-Chie Hung)*

洪明奇、陳曄

Disulfiram blocked cell entry of SARS-CoV-2 via inhibiting the interaction of spike protein and ACE2

American Journal of Cancer Research

 

2022

12

7

3333

3346

 

41

(Shih DJH)、(Chen MK)、(Yin J)、(McGrail DJ)、(Dai H)、(Wei R)、(Zhang J)、(Zheng WJ)、(Do KA)、(Yang L)、洪明奇(Mien-Chie Hung)、(Lin SY)*

洪明奇

Exploiting induced vulnerability to overcome PARPi resistance and clonal heterogeneity in BRCA mutant triple-negative inflammatory breast cancer

American Journal of Cancer Research

 

2022

12

1

337

357

 

42

(Xue Z)、(Zheng S)、(Linghu D)、(Liu B)、(Yang Y)、(Chen MK)、(Huang H)、(Song J)、(Li H)、(Wang J)、洪明奇(Mien-Chie Hung)、(Zhong D)、(Sun L)*

洪明奇

PD-L1 deficiency sensitizes tumor cells to DNA-PK inhibition and enhances cGAS-STING activation

American Journal of Cancer Research

 

2022

12

5

2363

2375

 

43

Parham Jabba、(Shima Shabani)、(Sagar Sharma)、(Minoo Partovi Nasr)、山口浩史(Yamaguchi Hirohito)*、洪明奇(Mien-Chie Hung)*

洪明奇

Shedding light on triple-negative breast cancer with Trop2-targeted antibody-drug conjugates

American Journal of Cancer Research

 

2022

12

4

1671

1685

 

44

張玲菊(Ling-Chu Chang)*、江世楷(Shih-Kai Chiang)、陳洵一(Shuen-Ei Chen)、洪明奇(Mien-Chie Hung)*

洪明奇

Targeting 2-oxoglutarate dehydrogenase for cancer treatment

American Journal of Cancer Research

 

2022

12

4

1436

1455

 

45

何俊德(Chun-Te Ho)、(SP-Lin)、(LM-Tseng)、洪明奇(Mien-Chie Hung)*、洪士杰(Shih-Chieh Hung)*

Mien-Chie Hung, Shih-Chieh Hung

Snail induces dormancy in disseminated luminal type A breast cancer through Src inhibition

American Journal of Cancer Research

1946-6234

2022

3

13

583

 

DOI:
10.1126/scitranslmed.abc2823

46

蕭連城(Lien-Cheng Hsiao)、林晏年(Yen-Nien Lin)、徐偉成(Woei-Cheang Shyu)、何銘(Ming- Ho)、盧炯睿(Chiung-Ray Lu)、張詩聖(Shih-Sheng Chang)、王宇澄(Yu-Chen Wang)、陳建佑(Jan-Yow Chen)、呂尚謁(Shang-yeh Lu)、吳美瑤(Mei-Yao Wu)、李庚原(Keng-Yuan Li)、林育楷(Yu-Kai Lin)、(Wen-Yih I. Tseng)、(Mao-Yuan Su)、(Chin-Ting Hsu)、(Cheng-Kang Tsai)、(Lu-Ting Chiu)、(Chien-Lin Chen)、林橙莉(Cheng-Li Lin)、胡凱傑、周德陽(Der-Yang Cho)、蔡長海(Chang-Hai Tsai)、張坤正(Kuan-Cheng Chang)*、鄭隆賓(Long-Bin Jeng)*

Woei-Cherng Shyu

First-in-Human Trial of Combined Intracoronary and Intravenous Transplantation of Mesenchymal Stem Cells for Heart Repair after Acute Myocardial Infarction.

Frontier in Cardiovascular Medicine

2297-055X

2022

9

 

961920

 

DOI: 10.3389/fcvm.2022.961920

47

(Shang-Yu Yang)、(Chi-Jung Fang)、(Yu-Wen Chen)、(Wan-Ping Chen)、(Li-Ya Lee)、(Chin-Chu Chen)、林彥佑、劉軒誌(Shan-Chi Liu)、蔡俊灝(Chun-Hao Tsai)、黃偉謙(Huang, Wei-Chien)、吳永昌(Yang-Chang Wu)、湯智昕(Chih-Hsin Tang)*

黃偉謙

Hericium erinaceus Mycelium Ameliorates In Vivo Progression of Osteoarthritis

Nutrients

 

2022

14

13

2605

 

DOI: 10.3390/nu14132605

48

Parveen N, Lin YL, Chou RH*, Sun CM*, Yu C*.

Chou RH

Synthesis of Novel Suramin Analogs With Anti-Proliferative Activity via FGF1 and FGFRD2 Blockade

Frontiers in Chemistry

2296-2646

2022

9

 

764200

 

DOI: 10.3389/fchem.2021.764200

49

Ju-Ying Lee, Wen-Ling Liao, Yu-Huei Liu, Chao-Lin Kuo, For-Wey Lung*, Ching-Liang Hsieh*

Yu-Huei Liu

Oral administration of processed Cassia obtusifolia L. seed powder May reduce body weight and cholesterol in overweight patients with schizophrenia: A 36-week randomized, double-blind, controlled trial of high and low doses

Journal of Ethnopharmacology

0378-8741

2022

292

 

115111

 

DOI: 10.1016/j.jep.2022.115111. Epub 2022 Mar 15.

50

陸自利(Lu, Tzu-Li)、佘玉萍(Yuh-Pyng Sher)、陳惠珍(Chen, Hui-Chen)、鄭維中(Cheng, Wei-Chung)、徐令恆、李珍珍(Chen-Chen Lee)*

李珍珍

Articulatin B chain induced dendritic cells maturation and driven type I T helper cells and cytotoxic T cells activation

Life Sciences

 

2022

302

 

120635

 

DOI: 10.1016/j.lfs.2022.120635

51

陳春忠(Chen,Chun-Chung)*、(Hong-Wei Li)、(Yuan-Liang wang)、李權峻(Chuan-Chun Lee)、沈怡均(Yi-Chun Shen)、謝清昀(Ching-Yun Hsieh)、林宏霖(Hung-Lin Lin)、陳賢修(XianXiu Chen)、周德陽(Der-Yang Cho)、謝慶良(Ching-Liang Hsieh)、郭政宏(Jeng-Hung Guo)、魏嵩泰、(John Wang)、(Shao-Chun Wang )*

周德陽

Patient‑derived tumor organoids as a platform of precision treatment for malignant brain tumors

Scientific Reports

 

2022

22

 

16399

 

DOI: 10.1038/s41598-022-20487-y

52

朱家聲(Chia-Sheng Chu)、楊其穎(Chi-Ying Yang)、葉俊杰(Chun-Chieh Yeh)、林若婷(Lin, Ro-Ting)、陳其敬(Chi-Ching Chen)、白禮源(Li-Yuan Bai)、洪明奇(Mien-Chie Hung)、林俊哲(LIN CHUN-CHE)、吳俊穎(Chun-Ying Wu)、林肇堂(LIN JAW-TOWN)*

洪明奇

Endoscopic ultrasound‑guided fine‑needle biopsy as a tool for studying the intra‑tumoral microbiome in pancreatic ductal adenocarcinoma: a pilot study

Scientific Reports

 

2022

 

 

 

 

DOI: 10.1038/s41598-021-04095-w

53

Yueh-Te Lin , Joseph Lin , Yi-En Liu , Kai-Wen Hsu , Chang-Chi Hsieh , Dar-Ren Chen , Han-Tsang Wu

Kai-Wen Hsu

Nafamostat mesylate overcomes endocrine resistance of breast cancer through epigenetic regulation of CDK4 and CDK6 expression.

Translational Oncology

1936-5233

2022

15

 

101302

 

DOI: 10.1016/j.tranon.2021.101302

54

Chung-Ling Liang, Ku-Chung Chen; Edward Hsi; Jui-Yu Lin; Chien-Yuan Chen; Jung-Kai Tseng; Suh-Hang Juo

 Chung-Ling Liang, Suh-Hang Juo

miR-328-3p affects axial length via multiple routes and anti-miR-328-3p possesses a potential to control myopia progression

 Invest Ophthalmol Vis Sci.

1552-5783

2022

In press

 

 

 

 

55

Kai-Fa Teo, Der-Yuan Chen, Jeh-Ting Hsu, Yi-Hua Lai, Ching-Kun Chang, Po-Ren Hsueh, Joung-Liang Lan, Jye-Lin Hsu

Jye-Lin Hsu

Screening and characterization of myositis-related autoantibodies in COVID-19 patients

Clinical and Translational Science

1752-8062

2022

In press

 

 

 

DOI: 10.1111/cts.13434

56

陳智皓(CHEN CHIH-HAO)、張坤正(Kuan-Cheng Chang)*、林晏年(Yen-Nien Lin)、何茂旺(Mao-Wang Ho)、鄭孟瑜(Meng-Yu Cheng)、施文心(HSIH WEN HSIN)、周家卉(Chia-Hui Chou)、林伯昌(Po-Chang Lin)、齊治宇(Chih-Yu Chi)、盧敏吉(Min-Chi Lu)、田霓(Ni Tien)、吳美瑤(Mei-Yao Wu)、張詩聖(Shih-Sheng Chang)、徐武輝(Wu-Huei Hsu)、徐偉成(Woei-Cheang Shyu)*、周德陽(Der-Yang Cho)、鄭隆賓(Long-Bin Jeng)*

周德陽

Mesenchymal Stem Cell Therapy on Top of Triple Therapy with Remdesivir, Dexamethasone, and Tocilizumab Improves PaO2/FiO2 in Severe COVID-19 Pneumonia

Frontiers in Medicine

 

2022

 

 

 

 

DOI: 10.3389/fmed.2022.1001979

57

(Hsiang-Lin Lee)、簡義忠(Chien, Yi-Chung)、(Hsiang-Ling Wang)、花俊宏(Chun-Hung Hua)、劉良智(Liang-Chih Liu)、吳國瑋(WU GUO-WEI)、白禮源(Li-Yuan Bai)*、(Shun-Fa Yang)*、余永倫(Yung-Luen Yu)*

余永倫

Analysis of MUC6 Genetic Variants on the Clinicopathologic Characteristics of Patients with Hepatocellular Carcinoma

Journal of Cancer

 

2022

13

11

3251

3257

DOI: 10.7150/jca.75754

58

Chang KH, Teng CJ, Hsu YC, Tsai SC, Lin HJ, Hsieh TL, Muo CH, Hsu CY, Chou RH*.

Chou RH

Long-Term Exposure to Air Pollution Associates the Risk of Benign Brain Tumor: A Nationwide, Population-Based, Cohort Study in Taiwan

Toxics

2305-6304

2022

10

4

176

 

DOI: 10.3390/toxics10040176

59

陳冠宇(Guan-Yu Chen)、潘奕澄、(Tung-Ying Wu)、(Tsung-You Yao)、王韋然(Wang, Wei-Jan)、(Wan-Jou Shen)、(Azaj Ahmed)、(Shu-Ting Chan)、湯智昕(Chih-Hsin Tang)、黃偉謙(Huang, Wei-Chien)、洪明奇(Mien-Chie Hung)、楊顓丞(Juan-Cheng Yang)*、吳永昌(Yang-Chang Wu)*

黃偉謙、洪明奇

Potential natural products that target the SARS-CoV-2 spike protein identified by structure-based virtual screening, isothermal titration calorimetry and lentivirus particles pseudotyped (Vpp) infection assay

Journal of Traditional and Complementary Medicine

 

2022

12

1

73

89

DOI: 10.1016/j.jtcme.2021.09.002

60

林秀姍(Hsiu-Hsien Lin)、曾坤浩(Kun-Hao Zeng)、田霓(Ni Tien)、林瑜姿(Yu-Tzu Lin)、游家鑫(Jiaxin Yu)、薛博仁(Hsueh, Po-Ren)、周德陽(Der-Yang Cho)*

周德陽

Evaluation of the Rapid Sepsityper protocol and specific MBT-Sepsityper module for the identification of bacteremia and fungemia using Bruker Biotyper MALDI-TOF MS

of Journal of Microbiology, Immunology and Infection

 

2022

 

 

 

 

DOI: 10.1016/j.jmii.2022.07.005

61

Che-Wei Liu, Eric Yuhsiang Wang, Hwai-Lee Wang, Kate Hsiurong Liao, Hsiao-Yun Chen, Hank Szuhan Chen, Ted Weita Lai

Ted Weita Lai

Blood-Brain Barrier Disruption in Preclinical Mouse Models of Stroke Can Be an Experimental Artifact Caused by Craniectomy

eNeuro

2373-2822

2022

9

5

ENEURO.0343-22.2022

 

DOI: 10.1523/ENEURO.0343-22.2022

62

Zhao FX, Chen W, Zhou H, Reinach PS, Wang Y, Juo SH, Yang Zl, Xue A, Shi Y, Liang CL,Zeng CQ, Qu J, Zhou XT

 Chung-Ling Liang, Suh-Hang Juo

PDE4B Proposed as a High Myopia Susceptibility Gene in Chinese Population

Front Genet

1664-8021

2022

1

12

775797

 

DOI: 10.3389/fgene.2021.775797

63

陳曄(Chen,Yeh)、楊文豪(Yang,Wen-Hao)、陳筱凡(Chen Hsiao-Fan)、(Huang LM)、(Gao JY)、林振文(Lin, Cheng-Wen)、(Wang YC)、(Yang CS)、(Liu YL)、(Hou MH)、(Tsai CL)、(Chou YZ)、(Bao-Yue Huang)、(Hung CF)、洪育琳(Hung, Yu-Lin)、王韋然(Wang, Wei-Jan)、蘇文琪(Wen-Chi Su)、(Kumar V)、(Wu YC)、(Chao SW)、(Chang CS)、(Chen JS)、(Chiang YP)、周德陽(Der-Yang Cho)、鄭隆賓(Long-Bin Jeng)、蔡長海(Chang-Hai Tsai)、洪明奇(Mien-Chie Hung)*

周德陽、陳曄、楊文豪、洪明奇

Tafenoquine and its derivatives as inhibitors for the severe acute respiratory syndrome coronavirus 2

Journal of biological chemistry

 

2022

298

3

101658

 

DOI: 10.1016/j.jbc.2022.101658

64

(Yang R)、(Sun L)、(Li CF)、(Wang YH)、(Xia W)、(Liu B)、(Chu YY)、(Bover L)、(Vien L)、洪明奇(Mien-Chie Hung)*

洪明奇

Development and characterization of anti-galectin-9 antibodies that protect T cells from galectin-9-induced cell death

Journal of biological chemistry

 

2022

298

4

101821

 

DOI: 10.1016/j.jbc.2022.101821

65

(Jong-Ho Cha)、(Li-Chuan Chan)、(Ying-Nai Wang)、(Yu-Yi Chu)、王啟鴻(Wang, Chie-Hong)、(Heng-Huan Lee)、(Weiya Xia)、徐偉成(Woei-Cheang Shyu)、劉詩平(Shih-Ping Liu)、(Jun Yao)、(Chiung-Wen Chang)、(Fan-Ru Cheng)、(Jielin Liu)、(Seung-Oe Lim)、(Jennifer L. Hsu)、楊文豪(Yang,Wen-Hao)、(Gabriel N. Hortobagyi)、(Chunru Lin)、(Liuqing Yang)、(Dihua Yu)、鄭隆賓(Long-Bin Jeng)*、洪明奇(Mien-Chie Hung)*

徐偉成、楊文豪、洪明奇

Ephrin receptor A10 monoclonal antibodies and the derived chimeric antigen receptor T cells exert an antitumor response in mouse models of triple-negative breast cancer

Journal of biological chemistry

 

2022

298

4

101817

101832

DOI: 10.1016/j.jbc.2022.101817

66

陳肇烜(Chao-Hsuan Chen)、(Pei-Chen Hsu)、(Shih-Wei Hsu)、(Kun-Ting Hong)、(Kai-Yuan Chen)、(Jie-Long He)、周德陽(Der-Yang Cho)、王韻琪(Wang, Yun-Chi)、張文馨(Wen-Shin Chang)、包大靝(Da-Tian Bau)*、蔡佳紋(Chia-Wen Tsai)*

周德陽

Protective Effects of Jujubosides on 6-OHDA-Induced Neurotoxicity in SH-SY5Y and SK-N-SH Cells

Molecules

 

2022

27

13

4106

 

DOI: 10.3390/molecules27134106

67

Hsin-Shui Chen, Yun-Chain Yau, Pin-Tsou Ko, Betty Lin-Ju Yen, Chun-Te Ho, Shih-Chieh Hung*

Shih-Chieh Hung

Mesenchymal stem cells from a hypoxic culture can improve rotator cuff tear repair

Cell Transplantation

0305-1048

2022

49

8

4725

4737

DOI: 10.1093/nar/gkab165

68

Achudhan Dav(Achudhan David)、張瓈云(Sunny LY Chang)、劉軒誌(Shan-Chi Liu)、林彥佑、黃偉謙(Huang, Wei-Chien)、吳永昌(Yang-Chang Wu)、黃建中(Huang, Chien-Chung)、蔡俊灝(Chun-Hao Tsai)、柯智淵(Chih-Yuan KO)、郭悅雄(Yueh-Hsiung Kuo)*、湯智昕(Chih-Hsin Tang)*

黃偉謙

Antcin K inhibits VCAM-1-dependent monocyte adhesion in human rheumatoid arthritis synovial fibroblasts

Food and Nutrition Research

 

2022

66

 

 

 

DOI: 10.29219/fnr.v66.8645

69

劉良智(Liang-Chih Liu)、簡義忠(Chien, Yi-Chung)、吳國瑋(WU, GUO-WEI)、花俊宏(Chun-Hung Hua)、蔡易臻(Tsai, I-Chen)、(Chih-Chiang Hung)、(Tsai-Kun Wu)、(Ying-Ru Pan)、(Shun-Fa Yang)*、余永倫(Yung-Luen Yu)*

余永倫

Analysis of EZH2 Genetic Variants on Triple-Negative Breast Cancer Susceptibility and Pathology

International Journal of Medical Sciences

 

2022

19

6

1023

1028

DOI: 10.7150/ijms.71931

70

(Chyou-Wei Wei)、(Tsai-Kun Wu)、(Shu-Cing Wu)、(Yi-Lin Chen)、(Ying-Ru Pan)、簡義忠(Chien, Yi-Chung)、吳佳燕、余永倫(Yung-Luen Yu)*、(Giou-Teng Yiang)*

余永倫

Curcumin enhances p-cresyl sulfate-induced cytotoxic effects on renal tubular cells

International Journal of Medical Sciences

 

2022

19

7

1138

1146

DOI: 10.7150/ijms.72646

71

Lin TF, Huang YJ, Liu YJ, Peng CM, Juan CJ, Yeh SH, Chou RH*.

Chou RH

3D-printed surgical wound dressing for prolonged 5-fluorouracil delivery from pluronic blending composites

Materials Today Communications

2352-4928

2022

33

 

104284

 

DOI: 10.1016/j.mtcomm.2022.104284

72

Che-Wei Liu,p Eric Yuhsiang Wang, Hwai-Lee Wang, Kate Hsiurong Liao, Hsiao-Yun Chen,Hank Szuhan Chen, and Ted Weita Lai

賴威達

Blood–Brain Barrier Disruption in Preclinical Mouse Models of Stroke Can Be an Experimental Artifact
Caused by Craniectomy

eNeuro

 

2022

9

5

 

 

DOI: 10.1523/ENEURO.0343-22.2022

73

Ching-Li Tseng, Shiun-Long Lin, Chung-Ling Liang, Suh-Hang Juo

 Chung-Ling Liang, Suh-Hang Juo

MicroRNA therapy for dry eye disease

J Ocul Pharmacol Ther

1080-7683

2022

38

2

125

132

DOI: 10.1089/jop.2021.0044

74

Ming-Lin Tsai,Chia-Hwa Lee,Li-Chi Huang,Yu-Hsin Chen,Wei-Ni Liu,Chun-Yu Lin,Kai-Wen Hsu,Ai-Wei Lee,Ching-Ling Lin

Kai-Wen Hsu

CRISPR-mediated knockout of VEGFR2/KDR inhibits cell growth in a squamous thyroid cancer cell line.

FEBS Open Bio

22115463

2022

12

993

1005

 

DOI: 10.1002/2211-5463.13399

75

(Kun-Tsan Lee)、蘇錦宏(Su, Chin-Horng)、劉軒誌(Shan-Chi Liu)、(Bo-Cheng Chen)、張郡崴(Chang, Jun-Way)、蔡俊灝(Chun-Hao Tsai)、黃偉謙(Huang, Wei-Chien)、許晉榮(Chin-Jung Hsu)、(Wei- Cheng Chen)、吳永昌(Yang-Chang Wu)、湯智昕(Chih-Hsin Tang)*

黃偉謙

Cordycerebroside A inhibits ICAM-1-dependent M1 monocyte adhesion to osteoarthritis synovial fibroblasts

Journal of Food Biochemistry

 

2022

46

7

 

 

DOI: 10.1111/jfbc.14108

76

王韋然(Wang, Wei-Jan)、陳曄(Chen,Yeh)、蘇文琪(Wen-Chi Su)、劉儼毅(Yen-Yi Liu)、(Wan-Jou Shen)、張為超(Wei-Chao Chang)、黃升騰(Sheng-Teng Huang)、林振文(Lin, Cheng-Wen)、(Yu-Chuan Wang)、楊佳昕(Chia-Shin Yang)、(Mei-Hui Hou)、(Yu-Chi Chou)、吳永昌(Yang-Chang Wu)、王紹椿(Shao-Chun Wang)、洪明奇(Mien-Chie Hung)*

王紹椿、陳曄、洪明奇

Peimine inhibits variants of SARS-CoV-2 cell entry via blocking the interaction between viral spike protein and ACE2

Journal of Food Biochemistry

 

2022

27

 

e14354

 

DOI: 10.1111/jfbc.14354

77

王韋然(Wang, Wei-Jan)、陳曄(Chen,Yeh)、蘇文琪(Wen-Chi Su)、劉儼毅(Yen-Yi Liu)、(Wan-Jou Shen)、張為超(Wei-Chao Chang)、黃升騰(Sheng-Teng Huang)、林振文(Lin, Cheng-Wen)、(Yu-Chuan Wang)、楊佳昕(Chia-Shin Yang)、(Mei-Hui Hou)、(Yu-Chi Chou)、吳永昌(Yang-Chang Wu)、王紹椿(Shao-Chun Wang)、洪明奇(Mien-Chie Hung)*

洪明奇、陳曄、王紹椿

Peimine inhibits variants of SARS-CoV-2 cell entry via blocking the interaction between viral spike protein and ACE2

Journal of Food Biochemistry

 

2022

27

 

e14354

 

DOI: 10.1111/jfbc.14354

78

侯甫葦(Pu-Wei Hou)、劉軒誌(Shan-Chi Liu)、蔡嘉哲(Gregory J. Tsay)、湯智昕(Chih-Hsin Tang)*、張恒鴻(Hen-Hong Chang)*

蔡嘉哲

The Traditional Chinese Medicine “Hu-Qian-Wan” Attenuates Osteoarthritis-Induced Signs and Symptoms in an Experimental Rat Model of Knee Osteoarthritis

Evidence-based Complementary and Alternative Medicine

 

2022

 

 

1

10

DOI: 10.1155/2022/5367494

79

何建宜(Chien-Yi Ho)、胡玳瑋、陳柏融(Chen, Bo-Rong)、(Chun-Chun Yang)、姚俊旭(Chun-Hsu Yao)、(Tien Ni)、(WEI-CHUAN HO)、陳悅生(Yueh-Sheng Chen)、涂智彥(Chih-Yen Tu)、張為超(Wei-Chao Chang)、吳永昌(Yang-Chang Wu)、湯智昕(Chih-Hsin Tang)、黃慧琪(Hui-Chi Huang)*、黃偉謙(Huang, Wei-Chien)*、(TZONG-SHIUN LI)*

黃偉謙

Snail Mucus Enhances Chemosensitivity of Triple-negative Breast Cancer Via Activation of the Fas Pathway

Anticancer Research

 

2022

42

2

845

855

DOI: 10.21873/anticanres.15542

80

沈運筑(Yun-Chu Shen)、石宏仁(Hung-Jen Shih)、林季千(Chi-Chien Lin)、黃勝賢(Sheng-Hsien Huang)、吳聖全(Sheng-Chuan Wu)、蕭志豪(Chi-Hao Hsiao)、邱紹智(Shao-Chih Chiu)、周德陽(Der-Yang Cho)、張進寶(Chin-Pao Chang)*、潘岳(Yueh Pan)*、施秉孝(Ping-Hsiao Shih)*

周德陽、邱紹智

Synergistic benefit of adoptive T cells in combination with chemoradiotherapy against metastatic prostate cancer cells,ANTICANCER RESEARCH,2022 Jun,42(7):3427-3434,SCI

Anticancer Research

 

2022

42

7

3427

3434

DOI: 10.21873/anticanres.15829

81

Zhao FX, Chen W, Zhou H, Reinach PS, Wang Y, Juo SH, Yang Zl, Xue A, Shi Y, Liang CL,Zeng CQ, Qu J, Zhou XT

 Chung-Ling Liang, Suh-Hang Juo

PDE4B Proposed as a High Myopia Susceptibility Gene in Chinese Population

Front Genet

1664-8021

2022

1

12

775797

 

DOI: 10.3389/fgene.2021.775797